Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2134732 | 0.83 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL28524216 | 0.82 | GAA (0.46) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL28993971 | 0.81 | GABRP (0.56) | POLBKDM4E | |
| SCHEMBL28532598 | 0.80 | LMNA (0.39) | ALDH1A1RAB9ANPC1L3MBTL1POLB | |
| SCHEMBL10174988 | 0.80 | RAB9A (0.56) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| Benzyl Carbamate SCHEMBL29186909 | 0.79 | ALDH1A1 (0.47) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL27925887 | 0.79 | ALDH1A1 (0.53) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL20954554 | 0.78 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL21841433 | 0.78 | RAB9A (0.50) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL28917643 | 0.78 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-116848099-A | Cyclin K degrading agent | 杭州阿诺生物医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-115772196-A | Compound with plasmin inhibitory activity, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| EP-0256990-A1 | Pyridinio compounds | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | disclosed |