Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.59 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.59 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690147 | 0.86 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10690539 | 0.85 | CNR1 (0.62) | TAAR1NPC1RAB9APLAAT5PLAAT4 | |
| SCHEMBL10695001 | 0.83 | ALDH1A1 (0.62) | NPC1RAB9APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10693892 | 0.82 | SMN1; SMN2 (0.57) | FPR2TAAR1NPC1GAARAB9A | |
| SCHEMBL744864 | 0.81 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL140038 | 0.79 | SMN1; SMN2 (0.67) | FPR2TAAR1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4583404 | 0.78 | SMN1; SMN2 (0.75) | FPR2TAAR1NPC1GAARAB9A | |
| SCHEMBL2335992 | 0.77 | KMT2A (0.71) | FPR2TAAR1NPC1GAARAB9A | |
| SCHEMBL2746054 | 0.77 | SMN1; SMN2 (0.65) | FPR2TAAR1NPC1GAARAB9A | |
| SCHEMBL3661534 | 0.77 | SMN1; SMN2 (0.60) | FPR2TAAR1NPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |