Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | FPR2 | P25090 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501899 | 0.90 | MMP8 (0.50) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL10693154 | 0.88 | NPC1 (0.54) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL10693248 | 0.86 | TAAR1 (0.49) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL10993323 | 0.85 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9APLAAT3PLAAT5 | |
| SCHEMBL10691686 | 0.82 | FPR2 (0.60) | SMN1; SMN2FPR2TAAR1NPC1GAA | |
| SCHEMBL10692779 | 0.82 | POLB (0.61) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL10694706 | 0.81 | POLB (0.56) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL10694773 | 0.78 | MAPT (0.46) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL10689506 | 0.77 | MMP8 (0.48) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL10691473 | 0.76 | RIPK1 (0.53) | SMN1; SMN2GAARAB9APTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |