Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.59 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.59 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993323 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPTPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10691686 | 0.83 | FPR2 (0.60) | ALDH1A1MAPTPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10223234 | 0.81 | CA12 (0.68) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL1968355 | 0.80 | CA12 (0.66) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL901614 | 0.80 | CA12 (0.73) | ALDH1A1MAPTPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10690539 | 0.79 | CNR1 (0.62) | ALDH1A1MAPTPLAAT5PLAAT4CA12 | |
| SCHEMBL16115911 | 0.79 | CA12 (0.64) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL2745785 | 0.79 | CA12 (0.64) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL29356619 | 0.79 | ALDH1A1 (0.77) | ALDH1A1MAPTCA1CA2CA9 | |
| SCHEMBL6270935 | 0.79 | ALDH1A1 (0.77) | ALDH1A1MAPTCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |