Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786824 | 0.77 | GSK3B (0.38) | HPGDTSHR | |
| SCHEMBL10693701 | 0.76 | SRD5A2 (0.38) | SRD5A2MAPK1HPGDNPC1HTT | |
| SCHEMBL10693391 | 0.75 | MAPK1 (0.41) | SRD5A2MAPK1HPGDNPC1HTT | |
| SCHEMBL10691708 | 0.73 | SRD5A2 (0.40) | SRD5A2MAPK1HPGDALDH1A1NPC1 | |
| SCHEMBL10691942 | 0.71 | XDH (0.49) | ALDH1A1NPC1KMT2AMAPTNPSR1 | |
| SCHEMBL6493919 | 0.68 | PARP1 (0.42) | KMT2ASMN1; SMN2 | |
| SCHEMBL17397034 | 0.68 | TTR (0.36) | MAPK1HPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9748582 | 0.67 | NR4A1 (0.44) | SRD5A2MAPK1HPGDKMT2AMAPT | |
| SCHEMBL9748600 | 0.67 | KMT2A (0.41) | SRD5A2MAPK1HPGDALDH1A1NPC1 | |
| SCHEMBL809735 | 0.66 | ATM (0.67) | SRD5A2MAPK1HPGDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |