Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692962 | 0.88 | ALDH1A1 (0.46) | MAPK1ELANESRD5A2HPGDMAPT | |
| SCHEMBL10691708 | 0.73 | SRD5A2 (0.40) | MAPK1HTTSRD5A2HPGDMAPT | |
| SCHEMBL10693391 | 0.73 | MAPK1 (0.41) | MAPK1HTTELANESRD5A2HPGD | |
| SCHEMBL9668299 | 0.68 | BRD4 (0.46) | MAPK1SRD5A2HPGDALDH1A1LMNA | |
| SCHEMBL7356037 | 0.67 | MAOA (0.43) | HPGDMAPTTDP1ALDH1A1KMT2A | |
| SCHEMBL18546949 | 0.66 | SRD5A2 (0.73) | MAPK1POLBSRD5A2MAPTALDH1A1 | |
| SCHEMBL51827 | 0.65 | SRD5A2 (0.80) | MAPK1HTTELANESRD5A2HPGD | |
| SCHEMBL9065412 | 0.65 | SRD5A2 (0.80) | MAPK1HTTELANESRD5A2HPGD | |
| SCHEMBL10697158 | 0.65 | SRD5A2 (0.80) | MAPK1HTTELANESRD5A2HPGD | |
| SCHEMBL1681512 | 0.65 | SRD5A2 (0.80) | MAPK1HTTELANESRD5A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |