Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689661 | 0.89 | ALDH1A1 (0.60) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL10692209 | 0.80 | NPC1 (0.60) | PTGDR2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10691153 | 0.80 | LMNA (0.48) | PTGDR2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10692046 | 0.78 | NPC1 (0.63) | PTGDR2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8545437 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL8546689 | 0.76 | ALDH1A1 (0.43) | PTGDR2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10691483 | 0.75 | FFAR1 (0.58) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL8546674 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL9750196 | 0.74 | KMT2A (0.50) | PTGDR2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8548073 | 0.74 | ALDH1A1 (0.43) | PTGDR2ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |