Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692209 | 0.87 | NPC1 (0.60) | NPC1MEN1KMT2APTGDR2SMN1; SMN2 | |
| SCHEMBL10691153 | 0.83 | LMNA (0.48) | NPC1MEN1KMT2APTGDR2SMN1; SMN2 | |
| SCHEMBL10691483 | 0.78 | FFAR1 (0.58) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10691802 | 0.78 | PTGDR2 (0.49) | NPC1MEN1KMT2APTGDR2SMN1; SMN2 | |
| SCHEMBL10690460 | 0.77 | LMNA (0.54) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9748038 | 0.76 | NPC1 (0.65) | NPC1MEN1KMT2APTGDR2SMN1; SMN2 | |
| SCHEMBL1492405 | 0.73 | LOXL2 (0.68) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10689661 | 0.71 | ALDH1A1 (0.60) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL25464938 | 0.70 | LOXL2 (0.68) | NPC1MEN1KMT2APTGDR2SMN1; SMN2 | |
| SCHEMBL30417629 | 0.70 | LOXL2 (0.68) | NPC1MEN1KMT2APTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |