Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690460 | 0.88 | LMNA (0.54) | LMNAHPGDPOLBPKMFFAR1 | |
| SCHEMBL10691483 | 0.87 | FFAR1 (0.58) | LMNAHPGDPOLBPKMFFAR1 | |
| SCHEMBL10692209 | 0.84 | NPC1 (0.60) | LMNAHPGDPOLBFFAR1MAPK1 | |
| SCHEMBL10689661 | 0.83 | ALDH1A1 (0.60) | LMNAHPGDPOLBPKMFFAR1 | |
| SCHEMBL10692046 | 0.83 | NPC1 (0.63) | LMNAPOLBFFAR1MAPK1MAPT | |
| SCHEMBL8547416 | 0.82 | MAPT (0.41) | LMNAHPGDPOLBPKMMAPT | |
| SCHEMBL4481950 | 0.80 | PTGDR2 (0.42) | LMNAPOLBFFAR1MAPTGFER | |
| SCHEMBL10691802 | 0.80 | PTGDR2 (0.49) | LMNAHPGDPOLBPKMFFAR1 | |
| SCHEMBL9749252 | 0.79 | GAA (0.51) | LMNAHPGDPOLBMAPTRAB9A | |
| SCHEMBL10691191 | 0.79 | ALDH1A1 (0.40) | LMNAPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |