Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693274 | 0.89 | HTR1B (0.47) | HTR1BNOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL10694997 | 0.87 | KDM4E (0.40) | SCN4AALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL10691821 | 0.81 | SMN1; SMN2 (0.50) | HTR1BALDH1A1LMNAMEN1MAPT | |
| SCHEMBL10690950 | 0.81 | HTR1B (0.50) | HTR1BALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL10926972 | 0.81 | ALDH1A1 (0.53) | SCN4AALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL10693265 | 0.79 | SLC6A4 (0.49) | HTR1BALDH1A1KDM4ESCN8ASLC6A4 | |
| SCHEMBL10696007 | 0.79 | HTR1B (0.45) | HTR1BNOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL6928489 | 0.79 | SCN4A (0.53) | SCN4AALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL3694800 | 0.76 | ALDH1A1 (0.41) | HTR1BALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL10695350 | 0.76 | ALDH1A1 (0.41) | HTR1BALDH1A1KDM4EHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |