Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 1.00 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329297 | 0.90 | ALOX5 (0.82) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL13792415 | 0.87 | ALOX5 (0.77) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL31329279 | 0.82 | ALOX5 (0.69) | ALOX5ALDH1A1POLB | |
| SCHEMBL31329298 | 0.81 | ALOX5 (0.68) | ALOX5ALDH1A1BCHEACHE | |
| SCHEMBL10697496 | 0.81 | ALOX5 (1.00) | ALOX5ALDH1A1 | |
| SCHEMBL659052 | 0.81 | ALOX5 (0.68) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL503646 | 0.81 | ALOX5 (0.68) | ALOX5F2RL1CALM1ALDH1A1 | |
| SCHEMBL1105476 | 0.81 | ALOX5 (0.68) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL31329305 | 0.80 | ALOX5 (0.67) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL8790474 | 0.80 | ALOX5 (0.66) | ALOX5F2RL1CALM1ALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |