Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693508 | 0.80 | KMT2A (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL11778068 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL8568846 | 0.78 | KMT2A (0.63) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL7233113 | 0.78 | KMT2A (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL11771414 | 0.77 | TP53 (0.38) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL8430657 | 0.76 | KMT2A (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL6626142 | 0.75 | KMT2A (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL28648791 | 0.75 | MEN1 (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL11794701 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL9655428 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |