Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430657 | 0.83 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL7233782 | 0.81 | CYP3A4 (0.38) | KMT2AMEN1CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL5143989 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1SMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL5718470 | 0.80 | RIPK1 (0.40) | SMN1; SMN2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL11839476 | 0.80 | CYP2A6 (0.41) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL10959895 | 0.79 | NPSR1 (0.50) | KMT2AMEN1SMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL7034982 | 0.79 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL6626142 | 0.78 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL10691887 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1SMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL9435677 | 0.76 | KMT2A (0.45) | KMT2AMEN1SMN1; SMN2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202981-A1 | SUBSTITUTED HETEROARYLOXYACETANILIDES AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-05-08 | — | — | EP | claimed |
| WO-2001005777-A1 | SUBSTITUTED HETEROARYLOXYACETANILIDES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-6544931-B1 | For controlling plant growth | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-08 | — | — | US | disclosed |
| EP-1202981-A1 | SUBSTITUTED HETEROARYLOXYACETANILIDES AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001005777-A1 | SUBSTITUTED HETEROARYLOXYACETANILIDES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |