Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689571 | 0.87 | MEN1 (0.51) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10692670 | 0.86 | SLC2A1 (0.50) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10693210 | 0.78 | SLC2A1 (0.59) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10689753 | 0.78 | ALDH1A1 (0.42) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10689340 | 0.75 | TP53 (0.42) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10775847 | 0.75 | SLC2A1 (0.45) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10693869 | 0.75 | SLC2A1 (0.45) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10693917 | 0.74 | KDM4E (0.44) | MEN1KMT2ACYP1A2CYP3A4TSHR | |
| SCHEMBL9312599 | 0.74 | MEN1 (0.69) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10691570 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2ATSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |