Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602219 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL10692017 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL10683157 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL5789435 | 0.72 | KDM4E (0.47) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL9602976 | 0.70 | KMT2A (0.45) | KDM4EALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL3715949 | 0.69 | KDM4E (0.56) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL31423348 | 0.69 | KDM4E (0.56) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL14300893 | 0.69 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL14932551 | 0.67 | BCHE (0.45) | KDM4EALDH1A1KMT2AGAAPPARD | |
| SCHEMBL4228872 | 0.66 | KDM4E (0.61) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782157-A | FROM CORRESPONDING ANHYDRIDES | AMERICAN CYANAMID CO. (US) | 1988-11-01 | — | — | US | disclosed |