Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685904 | 0.90 | APEX1 (0.43) | ALDH1A1SMN1; SMN2KDM4ECSNK2A2CSNK2A1 | |
| SCHEMBL10688331 | 0.80 | CYP1A2 (0.43) | ALDH1A1KDM4ECYP1A2CYP2C19PKM | |
| SCHEMBL9748006 | 0.77 | KDM4E (0.42) | ALDH1A1KDM4EPKM | |
| SCHEMBL9627261 | 0.76 | KDM4E (0.43) | ALDH1A1SMN1; SMN2KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL16593684 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EPKM | |
| SCHEMBL10691181 | 0.72 | PTPRG (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22550649 | 0.71 | KDM4E (0.46) | ALDH1A1KDM4ETSHRPKM | |
| SCHEMBL11603403 | 0.67 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4ECYP1A2CYP2E1 | |
| SCHEMBL9084114 | 0.65 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CSNK2A2CSNK2A1SLC6A5 | |
| SCHEMBL10685910 | 0.65 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4ECSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |