Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852499 | 0.86 | KMT2A (0.40) | KDM4EALDH1A1TDP1KMT2ARAB9A | |
| SCHEMBL10685904 | 0.81 | APEX1 (0.43) | KDM4EPOLBALDH1A1TDP1MAPT | |
| SCHEMBL9748006 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1TDP1HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL16593684 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1TDP1HPGDL3MBTL1 | |
| SCHEMBL10692166 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL16345888 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL10688331 | 0.71 | CYP1A2 (0.43) | KDM4EALDH1A1KMT2AL3MBTL1GAA | |
| SCHEMBL970781 | 0.70 | KDM4E (0.46) | KDM4EPOLBALDH1A1TDP1MAPT | |
| SCHEMBL10685641 | 0.70 | PTGS1 (0.39) | KDM4EALDH1A1KMT2AHPGDRAB9A | |
| SCHEMBL27766706 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091382-A | CEPHALOSPORIN DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |