Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685904 | 0.83 | APEX1 (0.43) | HSD17B10KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL9748006 | 0.82 | KDM4E (0.42) | HSD17B10KDM4EALDH1A1PKML3MBTL1 | |
| Hydrochloric Acid SCHEMBL16593684 | 0.81 | KDM4E (0.41) | HSD17B10KDM4EALDH1A1PKML3MBTL1 | |
| SCHEMBL10692166 | 0.80 | ALDH1A1 (0.44) | CYP1A2CYP2C19KDM4EALDH1A1PKM | |
| SCHEMBL22550649 | 0.76 | KDM4E (0.46) | CYP3A4KDM4EALDH1A1ALOX15PKM | |
| SCHEMBL9749314 | 0.75 | HSD17B10 (0.40) | CYP1A2CYP2C19HSD17B10CYP3A4KDM4E | |
| SCHEMBL9852499 | 0.73 | KMT2A (0.40) | HSD17B10KDM4EKMT2AFFAR1ALDH1A1 | |
| SCHEMBL10691181 | 0.73 | PTPRG (0.51) | CYP1A2CYP2C19KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9627261 | 0.71 | KDM4E (0.43) | KDM4EKMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL10688854 | 0.69 | HSD17B10 (0.43) | HSD17B10KDM4EKMT2AFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |