Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.65 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692770 | 0.90 | CTSB (0.73) | CTSBNOX4KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10692345 | 0.81 | CTSB (0.97) | CTSBNOX4KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10692339 | 0.81 | CTSB (0.97) | CTSBNOX4KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL922732 | 0.79 | CTSB (1.00) | CTSBNOX4KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9826473 | 0.71 | CTSB (0.63) | CTSBNOX4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL786831 | 0.70 | ALDH1A1 (0.56) | CTSBNOX4ALDH1A1SMN1; SMN2GPR35 | |
| SCHEMBL51277 | 0.70 | GPR35 (0.60) | CTSBNOX4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25416781 | 0.69 | CTSB (0.71) | CTSBNOX4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL22773553 | 0.69 | CTSB (0.71) | CTSBNOX4KCNJ1ALDH1A1SMN1; SMN2 | |
| SCHEMBL216753 | 0.68 | GPR35 (0.58) | CTSBNOX4ALDH1A1SMN1; SMN2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734376-A | SELECTIVE EXTRACTION AND COLORMETRIC DETERMINATION | THE PRESIDENT & TRUSTEES OF THE MIAMI UNIVERSITY (US) | 1988-03-29 | — | — | US | disclosed |
| US-4659815-A | Chromogenic aza-12-crown-4 ethers and method of using same for the detection of lithium | THE PRESIDENT AND TRUSTEES OF THE MIAMI UNIVERSITY (US) | 1987-04-21 | — | — | US | disclosed |