Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207495 | 0.85 | HDAC3 (0.48) | ALDH1A1HPGDHDAC3HDAC1HDAC4 | |
| SCHEMBL10690890 | 0.84 | HDAC3 (0.49) | ALDH1A1HPGDHDAC3HDAC1HDAC4 | |
| SCHEMBL7914371 | 0.83 | KDM4E (0.44) | ALDH1A1HPGDHDAC3HDAC1ADRA2B | |
| SCHEMBL9064516 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HPGDHDAC3HDAC1HDAC4 | |
| SCHEMBL10940633 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDGABRA1GABRB2MAPT | |
| SCHEMBL12900197 | 0.81 | TGM2 (0.50) | ALDH1A1HDAC3HDAC1ADRA2BADRA2C | |
| SCHEMBL30026550 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDGABRA1GABRB2MAPT | |
| SCHEMBL10693603 | 0.79 | SMN1; SMN2 (0.61) | ALDH1A1HPGDRAB9ANPC1MAPT | |
| SCHEMBL10692512 | 0.79 | HDAC3 (0.63) | ALDH1A1HPGDHDAC3HDAC1HDAC4 | |
| SCHEMBL9789600 | 0.79 | MAPT (0.58) | ALDH1A1HPGDHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |