Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837121 | 0.83 | VCP (1.00) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL13615748 | 0.77 | LMNA (0.56) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4387191 | 0.76 | RXFP1 (0.53) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL13615127 | 0.75 | ALDH1A1 (0.53) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL11540731 | 0.74 | ALDH1A1 (0.52) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL12303025 | 0.74 | KMT2A (0.51) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL15869563 | 0.73 | LMNA (0.63) | SMN1; SMN2ALDH1A1NPC1RAB9ARXFP1 | |
| SCHEMBL11540422 | 0.72 | ALDH1A1 (0.51) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL10503794 | 0.72 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9ARXFP1 | |
| SCHEMBL14303889 | 0.71 | LMNA (0.52) | VCPSMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760076-A | Inhibiting allergen-induced degranulation of peripheral leukocytes | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |