Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694467 | 0.86 | GAA (0.54) | GAATSHRALDH1A1LMNATP53 | |
| SCHEMBL10693889 | 0.80 | GAA (0.62) | GAATSHRALDH1A1LMNATP53 | |
| SCHEMBL22289326 | 0.80 | GAA (0.73) | GAATSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL10693228 | 0.77 | KMT2A (0.62) | PAMALDH1A1TP53MAPTNPC1 | |
| SCHEMBL11835262 | 0.76 | GAA (0.63) | GAATSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL3331879 | 0.74 | GAA (0.61) | GAATSHRALDH1A1LMNAMAPT | |
| SCHEMBL10692613 | 0.74 | PAM (0.64) | TSHRPAMALDH1A1POLBMAPT | |
| SCHEMBL10988833 | 0.73 | PDK1 (0.47) | GAATSHRTP53CYP3A4KMT2A | |
| SCHEMBL9090353 | 0.73 | ALDH1A1 (0.69) | PAMALDH1A1LMNAPOLBCYP3A4 | |
| SCHEMBL28807373 | 0.72 | GAA (0.70) | GAATSHRALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |