Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | EBP | Q15125 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692601 | 1.00 | SIGMAR1 (0.60) | SIGMAR1EBPKCNH2ADORA3CHRM1 | |
| SCHEMBL11099523 | 0.83 | SIGMAR1 (0.68) | SIGMAR1EBPKCNH2ADORA3CHRM1 | |
| SCHEMBL10694936 | 0.82 | SIGMAR1 (0.40) | SIGMAR1EBPKCNH2ADORA3CHRM1 | |
| SCHEMBL10694539 | 0.79 | SIGMAR1 (0.53) | SIGMAR1KCNH2TEAD1ALDH1A1 | |
| SCHEMBL10695755 | 0.78 | SIGMAR1 (0.55) | SIGMAR1KCNH2TEAD1ALDH1A1 | |
| Fenpropimorph SCHEMBL9020991 | 0.73 | SIGMAR1 (1.00) | SIGMAR1EBPKCNH2ADORA3CHRM1 | |
| Fenpropimorph SCHEMBL22362 | 0.73 | SIGMAR1 (1.00) | SIGMAR1EBPKCNH2ADORA3CHRM1 | |
| Fenpropimorph SCHEMBL22363 | 0.73 | SIGMAR1 (1.00) | SIGMAR1EBPKCNH2ADORA3CHRM1 | |
| Fenpropimorph SCHEMBL29455102 | 0.73 | SIGMAR1 (1.00) | SIGMAR1EBPKCNH2ADORA3CHRM1 | |
| Fenpropimorph SCHEMBL7953741 | 0.73 | SIGMAR1 (1.00) | SIGMAR1EBPKCNH2ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762826-A | FUNGICIDES FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | claimed |
| US-4762826-A | FUNGICIDES FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |