SCHEMBL10694936

SCHEMBL10694936

CC1CN(C[Si](C)(C)Cc2ccc([Si](C)(C)C)cc2)CC(C)O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.40
EBP Q15125 1/20 0.38
AGTR1 P30556 1/20 0.38
AGTR2 P50052 1/20 0.38
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.37
POLB P06746 1/20 0.36
GAA P10253 2/20 0.36
LMNA P02545 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD3 P35462 1/20 0.36
KCNH2 Q12809 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
CYP2A13 Q16696 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
MGAM O43451 1/20 0.35
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10692601 0.82 SIGMAR1 (0.60) SIGMAR1EBPAGTR1AGTR2ADORA3
SCHEMBL10692606 0.82 SIGMAR1 (0.60) SIGMAR1EBPAGTR1AGTR2ADORA3
SCHEMBL10693219 0.76 HRH3 (0.46) KDM4EHTTPOLBALDH1A1CYP2C19
SCHEMBL10929087 0.74 SIGMAR1 (0.69) SIGMAR1EBPKDM4EHTTPOLB
SCHEMBL10929081 0.74 SIGMAR1 (0.69) SIGMAR1EBPKDM4EHTTPOLB
SCHEMBL10696115 0.69 TSHR (0.47) AGTR1AGTR2KDM4EHTTGAA
SCHEMBL9633375 0.69 POLB (0.50) SIGMAR1EBPKDM4EHTTPOLB
SCHEMBL9631480 0.68 ALDH1A1 (0.49) SIGMAR1EBPKDM4EPOLBLMNA
SCHEMBL10872018 0.68 DRD2 (0.38) KDM4EHTTGAALMNATDP1
SCHEMBL12383 0.67 ALDH1A1 (0.55) SIGMAR1AGTR1AGTR2KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4762826-A FUNGICIDES FOR PLANTS CIBA-GEIGY CORPORATION (US) 1988-08-09 US disclosed