Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796358 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HSD17B10HTTL3MBTL1 | |
| SCHEMBL10918371 | 0.83 | FPR1 (0.52) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| SCHEMBL10693458 | 0.82 | FPR1 (0.48) | ALDH1A1L3MBTL1FPR1POLBNOTUM | |
| SCHEMBL10692647 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1HSD17B10HTTL3MBTL1 | |
| SCHEMBL10689596 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HSD17B10HTTL3MBTL1 | |
| SCHEMBL10691781 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HSD17B10HTTL3MBTL1 | |
| SCHEMBL10693527 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL10694565 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1HSD17B10HTTMAPT | |
| SCHEMBL10692445 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL10689558 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |