Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 known ✓ | Q07820 | 5/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 8/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488423 | 1.00 | SLC2A1 (0.39) | SLC2A1MCL1CD274NPBWR1KMT2A | |
| SCHEMBL10488421 | 1.00 | SLC2A1 (0.39) | SLC2A1MCL1CD274NPBWR1KMT2A | |
| SCHEMBL10488225 | 0.95 | CD274 (0.37) | SLC2A1MCL1CD274NPBWR1KMT2A | |
| SCHEMBL10692661 | 0.91 | MCL1 (0.33) | SLC2A1MCL1CD274 | |
| SCHEMBL10488246 | 0.82 | CD274 (0.40) | SLC2A1CD274NPBWR1KMT2AMCHR1 | |
| SCHEMBL29449853 | 0.82 | CD274 (0.40) | SLC2A1CD274NPBWR1KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL10488206 | 0.81 | CD274 (0.39) | SLC2A1CD274NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488332 | 0.79 | SLC2A1 (0.44) | SLC2A1CD274KMT2A | |
| SCHEMBL10488814 | 0.78 | SLC2A1 (0.35) | SLC2A1CD274NPBWR1KMT2AMCHR1 | |
| SCHEMBL10488890 | 0.78 | SLC2A1 (0.35) | SLC2A1CD274NPBWR1KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |