Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690936 | 0.88 | ALDH1A1 (0.56) | GAARAB9ANCOR2ALDH1A1KMT2A | |
| SCHEMBL10693447 | 0.85 | SMN1; SMN2 (0.54) | GAARAB9AABCB1HDAC1NCOR2 | |
| SCHEMBL10690219 | 0.84 | ALDH1A1 (0.59) | GAARAB9AABCB1HDAC1ALDH1A1 | |
| SCHEMBL10693467 | 0.83 | ABCB1 (0.55) | GAAABCB1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8284769 | 0.76 | HDAC3 (0.44) | GAAABCB1HDAC1HDAC3ALDH1A1 | |
| SCHEMBL8284763 | 0.75 | SLC16A3 (0.49) | ABCB1HDAC1HDAC3ALDH1A1KMT2A | |
| SCHEMBL10692512 | 0.74 | HDAC3 (0.63) | GAAHDAC1HDAC3ALDH1A1KMT2A | |
| SCHEMBL8803691 | 0.74 | SMN1; SMN2 (0.54) | GAARAB9AABCB1ALDH1A1KMT2A | |
| SCHEMBL3555921 | 0.73 | ALDH1A1 (0.65) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4681910 | 0.73 | ALDH1A1 (0.62) | GAARAB9ANCOR2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |