Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | GRK2 | P25098 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692720 | 0.88 | GAA (0.57) | ALDH1A1GAAKMT2APOLBGRK2 | |
| SCHEMBL4681910 | 0.86 | ALDH1A1 (0.62) | ALDH1A1GAAKMT2APOLBGRK2 | |
| SCHEMBL28220176 | 0.86 | ALDH1A1 (0.58) | ALDH1A1GAAKMT2APOLBGRK2 | |
| SCHEMBL10693527 | 0.84 | SMN1; SMN2 (0.59) | ALDH1A1GAAKMT2APOLBGRK2 | |
| SCHEMBL10690887 | 0.84 | L3MBTL1 (0.64) | ALDH1A1GAAKMT2APOLBRAB9A | |
| SCHEMBL10691682 | 0.81 | NPC1 (0.53) | ALDH1A1GAAKMT2ARAB9AL3MBTL1 | |
| SCHEMBL10693682 | 0.81 | L3MBTL1 (0.50) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| SCHEMBL7154513 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KMT2AL3MBTL1MEN1TSHR | |
| SCHEMBL10692512 | 0.75 | HDAC3 (0.63) | ALDH1A1GAAKMT2APOLBGRK2 | |
| SCHEMBL28251912 | 0.75 | LTA4H (0.72) | KMT2ARAB9AL3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |