SCHEMBL10692728

SCHEMBL10692728

Cc1ccccc1S(=O)(=O)N(CO)CO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR2 O43614 1/20 0.48
PTPN1 P18031 1/20 0.47
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
KMT2A Q03164 2/20 0.42
HSD11B1 P28845 2/20 0.41
ALDH1A1 P00352 2/20 0.39
HTT P42858 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
GAA P10253 2/20 0.38
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
NSD2 O96028 1/20 0.37
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683547 0.85 SMN1; SMN2 (0.46) HCRTR2PTPN1HTR2AHTR2CKMT2A
SCHEMBL10597185 0.84 ALDH1A1 (0.43) HCRTR2PTPN1KMT2AALDH1A1HTT
SCHEMBL10693742 0.83 HCRTR2 (0.47) HCRTR2PTPN1HTR2AHTR2CKMT2A
SCHEMBL9001236 0.82 ALDH1A1 (0.54) HCRTR2KMT2AALDH1A1HTTHPGD
SCHEMBL3693999 0.80 TSHR (0.49) HCRTR2PTPN1KMT2AALDH1A1ESR1
SCHEMBL6388216 0.78 PTPN1 (0.42) HCRTR2PTPN1HTR2AHTR2CKMT2A
SCHEMBL5505271 0.78 CA12 (0.48) HCRTR2PTPN1KMT2AALDH1A1ESR1
SCHEMBL9307793 0.78 ALDH1A1 (0.47) HCRTR2PTPN1KMT2AALDH1A1TDP1
SCHEMBL2583710 0.78 TSHR (0.57) HCRTR2PTPN1KMT2AALDH1A1HTT
SCHEMBL28185888 0.77 RAB9A (0.48) HCRTR2PTPN1HTR2AHTR2CKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4764570-A MODIFYING MELAMINE-FORMALDEHYDE RESINS CASSELLA AKTIENGESELLSCHAFT (DE) 1988-08-16 US disclosed