Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200353 | 0.86 | ALDH1A1 (0.53) | HCRTR2HTR2AHTR2CLMNAKMT2A | |
| SCHEMBL10597180 | 0.84 | ALDH1A1 (0.42) | HCRTR2LMNAHPGDALDH1A1POLB | |
| SCHEMBL11242851 | 0.84 | POLB (0.56) | HCRTR2HTR2AHTR2CLMNAKMT2A | |
| SCHEMBL4566032 | 0.83 | HCRTR2 (0.48) | HCRTR2HTR2AHTR2CLMNAKMT2A | |
| SCHEMBL10692728 | 0.83 | HCRTR2 (0.48) | HCRTR2HTR2AHTR2CKMT2AHSD11B1 | |
| SCHEMBL15829877 | 0.80 | HTR2A (0.44) | HCRTR2HTR2AHTR2CLMNAKMT2A | |
| SCHEMBL10587159 | 0.79 | KMT2A (0.61) | LMNAKMT2AHPGDALDH1A1POLB | |
| SCHEMBL17303556 | 0.79 | HTR2A (0.43) | HCRTR2HTR2AHTR2CLMNAKMT2A | |
| SCHEMBL701463 | 0.78 | ALDH1A1 (0.55) | HCRTR2HTR2AHTR2CLMNAHSD11B1 | |
| SCHEMBL9683547 | 0.76 | SMN1; SMN2 (0.46) | HCRTR2HTR2AHTR2CKMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764570-A | MODIFYING MELAMINE-FORMALDEHYDE RESINS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |