Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577212 | 0.78 | ALOX15 (0.52) | ALOX15GAAPKMHSD17B10CYP1A2 | |
| SCHEMBL18529269 | 0.77 | GAA (0.50) | ALOX15GAAPKMHSD17B10CYP1A2 | |
| SCHEMBL10878953 | 0.76 | ALOX15 (0.48) | ALOX15GAAPKMHSD17B10CYP1A2 | |
| SCHEMBL11370831 | 0.72 | CA2 (0.53) | ALOX15GAAPKMHSD17B10PIK3CG | |
| SCHEMBL3208200 | 0.69 | — | — | |
| SCHEMBL5216438 | 0.69 | CCNE1 (0.48) | CCNE1CDK2CDK1CDK4ADORA1 | |
| SCHEMBL9749986 | 0.68 | LMNA (0.49) | ALOX15GAAPKMHSD17B10APOBEC3A | |
| Acetic Acid SCHEMBL5212685 | 0.67 | CCNE1 (0.47) | L3MBTL1OGACCNE1CDK2CDK1 | |
| SCHEMBL4292895 | 0.67 | HCAR2 (0.42) | ALOX15GAAHSD17B10MAPK1L3MBTL1 | |
| SCHEMBL31156399 | 0.65 | SMN1; SMN2 (0.50) | HSD17B10CYP1A2L3MBTL1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |