Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | STK17B | O94768 | 2/20 | 0.41 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 3/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.39 |
| ▸ | CCND1 | P24385 | 3/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878953 | 0.80 | ALOX15 (0.48) | GAAL3MBTL1ALOX15HSD17B10PKM | |
| SCHEMBL9749393 | 0.80 | SMN1; SMN2 (0.40) | GAAL3MBTL1HSD17B10HPGDRAB9A | |
| SCHEMBL2666164 | 0.73 | CCNE1 (0.69) | GAACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL9748847 | 0.71 | L3MBTL1 (0.45) | GAAL3MBTL1MAP3K8HSD17B10HPGD | |
| SCHEMBL15577212 | 0.70 | ALOX15 (0.52) | GAAL3MBTL1ALOX15HSD17B10PKM | |
| SCHEMBL18529269 | 0.68 | GAA (0.50) | GAAL3MBTL1ALOX15HSD17B10PKM | |
| SCHEMBL10692730 | 0.68 | ALOX15 (0.50) | GAAL3MBTL1ALOX15HSD17B10PKM | |
| SCHEMBL10361186 | 0.66 | SMN1; SMN2 (0.42) | HSD17B10RAB9APOLB | |
| SCHEMBL8436040 | 0.65 | GAA (0.74) | GAAL3MBTL1HSD17B10HPGDPOLB | |
| SCHEMBL11370831 | 0.64 | CA2 (0.53) | GAAALOX15HSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |