SCHEMBL3077407

SCHEMBL3077407

Nc1cc(S(=O)(=O)c2ccc(Cl)c(N)c2)ccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
GAA P10253 3/20 0.57
ALDH1A1 P00352 4/20 0.55
PKM P14618 3/20 0.55
HTR6 P50406 2/20 0.55
NPSR1 Q6W5P4 1/20 0.53
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA9 Q16790 4/20 0.50
CA12 O43570 3/20 0.50
TSHR P16473 3/20 0.50
CA7 P43166 2/20 0.50
CA14 Q9ULX7 2/20 0.50
TP53 P04637 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932826 1.00 MAPT (0.57) MAPTGAAALDH1A1PKMHTR6
SCHEMBL12639373 0.92 MEN1 (0.62) MAPTGAAALDH1A1PKMHTR6
SCHEMBL4615892 0.90 HTR6 (0.52) MAPTGAAALDH1A1PKMHTR6
SCHEMBL3284674 0.89 GAA (0.57) MAPTGAAALDH1A1PKMHTR6
SCHEMBL1186046 0.84 CA2 (0.70) MAPTGAAALDH1A1PKMNPSR1
SCHEMBL27538809 0.84 MAPT (0.51) MAPTGAAALDH1A1PKMHTR6
SCHEMBL341943 0.83 ALDH1A1 (0.62) MAPTGAAALDH1A1PKMNPSR1
SCHEMBL1370002 0.83 LMNA (0.55) MAPTALDH1A1PKMNPSR1CA1
SCHEMBL27781331 0.83 MAPT (0.50) MAPTGAAALDH1A1PKMHTR6
SCHEMBL7769124 0.83 MAPT (0.50) MAPTGAAALDH1A1PKMHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US claimed
CN-108445060-B Preparation method of sensor electrode for detecting formaldehyde content in air 广东华晟安全职业评价有限公司 2020-02-14 CN disclosed
US-9715144-B2 Photoalignment composition ROLIC AG (CH) 2017-07-25 US disclosed
CN-105524267-A Random polymers with framework containing ammonium and phosphonic acid groups, and preparation method thereof UNIV TIANJIN 2016-04-27 CN disclosed
CN-105131290-A Alternating polymers having skeleton containing ammonium and sulfonate zwitterionic groups and preparation method thereof UNIV TIANJIN NORMAL 2015-12-09 CN disclosed
CN-105131276-A Random polymers having skeleton containing ammonium and sulfonate zwitterionic groups and preparation method thereof UNIV TIANJIN NORMAL 2015-12-09 CN disclosed
EP-1260498-B1 NOVEL COLOR FORMER AND RECORDING MATERIAL CHEMIPRO KASEI KAISHA LTD (JP) 2014-07-09 EP disclosed
CN-101003499-B Novel color former and recording material ASAHI CHEMICAL IND 2011-01-19 CN disclosed
US-20100266814-A1 PHOTOALIGNMENT COMPOSITION ROLIC AG (CH) 2010-10-21 US disclosed
US-7807738-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2010-10-05 US disclosed
US-5093305-A Phenolic Compound, Aromatic Isocyanate, Imine MITSUBISHI PAPER MILLS LIMITED (JP) 1992-03-03 US disclosed
US-5079211-A Reduced fogging, image storage stability, thermal printing MITSUBISHI PAPER MILLS LIMITED (JP) 1992-01-07 US disclosed
US-5043315-A Aromatic or heterocyclic isocyanate and imino compound MITSUBISHI PAPER MILLS LIMITED (JP) 1991-08-27 US disclosed
US-5043312-A Mixture of imino and isocyanate compounds, biphenyl alcohol in binder on support; image preservation, heat responsiveness MITSUBISHI PAPER MILLS LIMITED (JP) 1991-08-27 US disclosed
EP-0439638-A1 Heat sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1991-08-07 EP disclosed
US-5036039-A Aromatic isocyanate and imine MITSUBISHI PAPER MILLS LIMITED (JP) 1991-07-30 US disclosed
EP-0427929-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1991-05-22 EP disclosed
US-4965237-A AROMATICITY-POSESSING ISOCYANATE COMPOUND, IMINO COMPOUND, AND ANILINE DERIVATIVE MITSUBISHI PAPER MILLS, LTD. (JP) 1990-10-23 US disclosed
US-4204056-A Process and intermediates for preparing fiber-reactive phthalocyanine dyes CASSELLA AKTIENGESELLSCHAFT (DE) 1980-05-20 US disclosed
US-4191686-A FROM SULFONYL HALIDE SUBSTITUTED PARENT BY AMIDATION WITH AROMATIC DIAMINE, DIAZOTIZING, COUPLING TO KETO SUCCINIC ESTER, CYCLIZING, COUPLING TO REACTIVE MOIETY CASSELLA AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed