Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29229 | 0.75 | LMNA (0.44) | POLBCA12CA1CA2CA9 | |
| SCHEMBL21776576 | 0.75 | MCL1 (0.39) | POLBGPR35KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8330002 | 0.72 | GPR35 (0.53) | POLBGPR35KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11668702 | 0.71 | ACACB (0.33) | KMT2A | |
| SCHEMBL28770248 | 0.71 | DAO (0.32) | POLBALDH1A1TSHRAPEX1TDP1 | |
| SCHEMBL4246332 | 0.70 | POLB (0.47) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29720895 | 0.70 | ALDH1A1 (0.39) | CA12CA1CA2CA9KDM4E | |
| Methoxymethane SCHEMBL7593741 | 0.70 | KDM4E (0.34) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2495583 | 0.69 | GPR35 (0.39) | POLBGPR35CA12CA1CA2 | |
| SCHEMBL780340 | 0.68 | GPR35 (0.38) | POLBGPR35CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764518-A | Antibacterial agents containing oxo-4-pyridine carboxylic acid derivatives | PANMEDICA (FR) | 1988-08-16 | — | — | US | disclosed |