Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692456 | 0.75 | GRM1 (0.38) | MGLLSMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL10693172 | 0.75 | KMT2A (0.38) | MGLLSMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL10693327 | 0.73 | XDH (0.49) | LMNAGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL28953638 | 0.64 | ALDH1A1 (0.62) | SMN1; SMN2LMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL8895195 | 0.64 | SMN1; SMN2 (0.64) | MGLLKDM2BSMN1; SMN2LMNAGAA | |
| SCHEMBL16058772 | 0.64 | PBRM1 (0.42) | LMNAALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL14067799 | 0.64 | NPSR1 (0.49) | MGLLKDM2BSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8367098 | 0.62 | PRMT5 (0.44) | KDM2BSMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL6183451 | 0.60 | ALDH1A1 (0.61) | MGLLSMN1; SMN2ALDH1A1KMT2ACYP2D6 | |
| SCHEMBL13268159 | 0.60 | NPC1 (0.46) | MGLLLMNAKMT2ACYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |