Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944266 | 0.87 | ANPEP (0.52) | ANPEPDNPEPHPGDLMNAPKM | |
| Trifluoroacetic Acid SCHEMBL28343191 | 0.78 | ALDH1A1 (0.39) | LMNASMN1; SMN2RAB9AL3MBTL1CNR1 | |
| SCHEMBL20813199 | 0.77 | HPGD (0.54) | ANPEPDNPEPHPGDLMNAPKM | |
| SCHEMBL22844861 | 0.76 | HPGD (0.41) | ANPEPDNPEPHPGDLMNAPKM | |
| Trifluoroacetic Acid SCHEMBL13519111 | 0.76 | MCL1 (0.38) | SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7947948 | 0.76 | KMT2A (0.41) | ANPEPDNPEPHPGDLMNAPKM | |
| Trifluoroacetic Acid SCHEMBL6225952 | 0.75 | GABRR1 (0.48) | LMNASMN1; SMN2RAB9A | |
| Trifluoroacetic Acid SCHEMBL7711992 | 0.75 | NPC1 (0.33) | HPGDLMNASMN1; SMN2HTTRAB9A | |
| SCHEMBL7936587 | 0.74 | KMT2A (0.45) | ANPEPDNPEPHPGDLMNAPKM | |
| SCHEMBL5486728 | 0.74 | SMN1; SMN2 (0.58) | ANPEPDNPEPLMNAPKMRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |