Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677768 | 0.89 | KDM4E (0.50) | TACR3KDM4EALDH1A1HTTAPAF1 | |
| SCHEMBL10678422 | 0.82 | ALDH1A1 (0.40) | TACR3KDM4EALDH1A1HTTMAPT | |
| SCHEMBL1284854 | 0.79 | CTNNB1 (0.54) | HTTL3MBTL1MTNR1AMMP9MMP8 | |
| Hydrochloric Acid SCHEMBL10692591 | 0.78 | DHODH (0.51) | TACR3KDM4E | |
| SCHEMBL10676621 | 0.73 | MEN1 (0.48) | KDM4EALDH1A1MAPTRECQLMTNR1A | |
| SCHEMBL26167691 | 0.72 | SRR (0.54) | MMEACECPA1ACE2 | |
| SCHEMBL15345674 | 0.72 | HTR2A (0.48) | KDM4EALDH1A1MAPTPTGS1 | |
| SCHEMBL31036986 | 0.71 | PPARG (0.50) | MMEACECPA1ACE2 | |
| SCHEMBL8054334 | 0.69 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL8054347 | 0.69 | PRKCZ (0.41) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |