Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 3/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 3/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693439 | 0.84 | CNR2 (0.48) | CNR2TBXAS1CNR1KRASICMT | |
| SCHEMBL7679351 | 0.81 | ALDH1A1 (0.62) | ICMTALDH1A1LMNAPLA2G2A | |
| SCHEMBL7682923 | 0.80 | ICMT (0.54) | CNR2TBXAS1CNR1KRASICMT | |
| SCHEMBL4668108 | 0.78 | TBXAS1 (0.44) | CNR2TBXAS1CNR1ALDH1A1LMNA | |
| SCHEMBL9236079 | 0.78 | CDC25A (0.70) | CNR2CNR1ICMTCDC25A | |
| SCHEMBL8181539 | 0.77 | CDC25A (0.52) | CNR2TBXAS1CNR1KRASICMT | |
| SCHEMBL22439063 | 0.77 | ICMT (0.48) | CNR2TBXAS1CNR1KRASICMT | |
| SCHEMBL8176472 | 0.77 | ALDH1A1 (0.55) | CNR2ICMTALDH1A1LMNAPLA2G2A | |
| SCHEMBL8173706 | 0.76 | KEAP1 (0.48) | CNR2TBXAS1CNR1AKR1A1AKR1B1 | |
| SCHEMBL8171679 | 0.76 | ALDH1A1 (0.54) | TBXAS1ICMTALDH1A1LMNAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |