SCHEMBL10693456

SCHEMBL10693456

Nc1c(Br)cc(S(=O)(=O)c2ccccc2)cc1Br

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.57
CA2 P00918 7/20 0.57
CA9 Q16790 6/20 0.57
CA3 P07451 2/20 0.57
HTR6 P50406 6/20 0.56
CA12 O43570 3/20 0.46
CA7 P43166 3/20 0.46
CA13 Q8N1Q1 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
PLA2G7 Q13093 1/20 0.46
LMNA P02545 2/20 0.45
PIK3CA P42336 1/20 0.42
PIK3C3 Q8NEB9 1/20 0.42
MPO P05164 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5981611 0.87 CA2 (0.73) CA1CA2CA9CA3HTR6
SCHEMBL11216559 0.81 CA1 (0.63) CA1CA2CA9CA3HTR6
SCHEMBL23589558 0.79 CA1 (0.50) CA1CA2CA9CA3HTR6
SCHEMBL10694631 0.78 HTR6 (0.50) CA1CA2CA9CA3HTR6
SCHEMBL1332008 0.78 HTR6 (0.82) CA1CA2CA9CA3HTR6
SCHEMBL7206333 0.78 HTR6 (0.58) CA1CA2CA9CA3HTR6
SCHEMBL10363195 0.77 HTR6 (0.64) CA1CA2CA9CA3HTR6
(Phenylsulfonyl)Benzene SCHEMBL28730795 0.75 HTR6 (0.88) CA1CA2CA9CA3HTR6
(Phenylsulfonyl)Benzene SCHEMBL27791085 0.75 HTR6 (0.88) CA1CA2CA9CA3HTR6
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.75 HTR6 (1.00) CA1CA2CA9CA3HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed