SCHEMBL10694631

SCHEMBL10694631

Nc1c(Br)cc(Br)cc1S(=O)(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 6/20 0.50
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA3 P07451 2/20 0.41
CA9 Q16790 2/20 0.41
GAA P10253 3/20 0.41
POLB P06746 1/20 0.41
GFER P55789 1/20 0.41
CA12 O43570 2/20 0.41
CA7 P43166 2/20 0.41
CA13 Q8N1Q1 2/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
PLA2G7 Q13093 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11815362 0.79 ALDH1A1 (0.51) HTR6ALDH1A1KDM4ECA1CA2
SCHEMBL10693456 0.78 CA1 (0.57) HTR6ALDH1A1KDM4ECA1CA2
SCHEMBL13406869 0.78 HTR6 (0.53) HTR6ALDH1A1KDM4EGAAPOLB
SCHEMBL226516 0.77 HTR6 (0.48) HTR6ALDH1A1KDM4ECA1CA2
SCHEMBL11137429 0.76 CA1 (0.42) CA1CA2CA3CA9CA4
SCHEMBL5624674 0.75 CA2 (0.52) ALDH1A1KDM4ECA1CA2CA3
SCHEMBL11139152 0.73 KDM4E (0.48) ALDH1A1KDM4ECA9CA12PKM
SCHEMBL229081 0.73 HTR6 (0.48) HTR6ALDH1A1KDM4EGAAPOLB
SCHEMBL459805 0.73 HTR6 (0.60) HTR6ALDH1A1KDM4ECA1CA2
SCHEMBL11129764 0.72 CA2 (0.43) ALDH1A1KDM4ECA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed