Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.36 |
| ▸ | WNT3A | P56704 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693893 | 0.89 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDCTNNB1WNT3A | |
| SCHEMBL10691793 | 0.86 | HPGD (0.48) | ALDH1A1HPGDCTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL10688132 | 0.79 | DRD4 (0.46) | ALDH1A1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8785344 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDCTNNB1WNT3A | |
| SCHEMBL10692456 | 0.77 | GRM1 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRNPC1 | |
| SCHEMBL10692784 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL9437812 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDCTNNB1WNT3A | |
| SCHEMBL10694710 | 0.68 | XDH (0.49) | ALDH1A1LMNAMAPTTDP1PKM | |
| SCHEMBL10693647 | 0.67 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDCTNNB1WNT3A | |
| SCHEMBL10693708 | 0.66 | THRA (0.38) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |