Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 12/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692155 | 0.86 | SLC2A1 (0.50) | HTR1BALDH1A1KDM4ESLC2A1SLC6A4 | |
| SCHEMBL10692922 | 0.83 | HTR1B (0.56) | HTR1BSCN8ASLC2A1SLC6A4CYP1A2 | |
| SCHEMBL10692538 | 0.82 | ALDH1A1 (0.42) | HTR1BALDH1A1KDM4ESCN8ASLC6A4 | |
| SCHEMBL10696007 | 0.81 | HTR1B (0.45) | HTR1BALDH1A1KDM4ESCN8ASLC6A4 | |
| SCHEMBL10692959 | 0.79 | HTR1B (0.56) | HTR1BALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL8858374 | 0.79 | KDM4E (0.69) | ALDH1A1KDM4ESCN8A | |
| SCHEMBL10693962 | 0.73 | HPGD (0.48) | ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL1773810 | 0.72 | HTR1B (0.80) | HTR1BALDH1A1KDM4ESLC6A4HPGD | |
| SCHEMBL27603617 | 0.72 | CNR1 (0.41) | HTR1BALDH1A1KDM4ESLC2A1CYP1A2 | |
| SCHEMBL23089937 | 0.71 | TLR8 (0.46) | HTR1BSLC2A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |