Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 5/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692155 | 0.94 | SLC2A1 (0.50) | HTR1BSLC2A1SLC6A4HRH1ADRB2 | |
| SCHEMBL10693568 | 0.83 | HTR1B (0.47) | HTR1BSLC2A1SLC6A4SCN8ACYP1A2 | |
| SCHEMBL293401 | 0.81 | SLC2A1 (0.48) | HTR1BSLC2A1HTR1DCYP1A2CYP2D6 | |
| SCHEMBL29368652 | 0.81 | SLC2A1 (0.48) | HTR1BSLC2A1HTR1DCYP1A2CYP2D6 | |
| SCHEMBL23089937 | 0.80 | TLR8 (0.46) | HTR1BSLC2A1CYP1A2CYP2D6 | |
| SCHEMBL29368699 | 0.80 | TLR8 (0.46) | HTR1BSLC2A1CYP1A2CYP2D6 | |
| SCHEMBL29371827 | 0.79 | TLR8 (0.44) | HTR1BSLC2A1KMT2AHTR1DCYP1A2 | |
| SCHEMBL7966951 | 0.79 | TLR8 (0.44) | HTR1BSLC2A1KMT2AHTR1DCYP1A2 | |
| SCHEMBL7877916 | 0.78 | GPR84 (0.47) | HTR1BKMT2ACYP1A2MAPK1CYP2C19 | |
| SCHEMBL23089944 | 0.78 | TLR8 (0.48) | HTR1BSLC2A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |