Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866552 | 0.71 | TSHR (0.43) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL9866994 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL9868777 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL9867546 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL10693575 | 0.67 | ALDH1A1 (0.42) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL9867123 | 0.67 | ALDH1A1 (0.39) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL1202828 | 0.67 | ALDH1A1 (0.58) | TSHRALDH1A1KDM4EESR1HPGD | |
| SCHEMBL28055932 | 0.65 | CHRNB2 (0.49) | ALDH1A1KDM4ERAB9AL3MBTL1ESR1 | |
| SCHEMBL9868767 | 0.64 | KDM4E (0.43) | TSHRALDH1A1KDM4ERAB9AGAA | |
| Hydrazine SCHEMBL18138498 | 0.64 | ALDH1A1 (0.55) | TSHRALDH1A1KDM4EESR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266060-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-05-04 | — | — | EP | disclosed |