Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 4/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365546 | 0.74 | TSHR (0.47) | ALDH1A1GAATSHRKDM4ERAB9A | |
| SCHEMBL9867553 | 0.70 | CHRM2 (0.41) | ALDH1A1GAATSHRKDM4ERAB9A | |
| SCHEMBL9866552 | 0.69 | TSHR (0.43) | ALDH1A1GAATSHRKDM4ERAB9A | |
| SCHEMBL9867546 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GAATSHRKDM4ERAB9A | |
| SCHEMBL9868777 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GAATSHRKDM4ERAB9A | |
| SCHEMBL9866994 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GAATSHRKDM4ERAB9A | |
| SCHEMBL3071211 | 0.68 | TSHR (0.53) | ALDH1A1TSHRKDM4ECRHBPCRHR2 | |
| SCHEMBL5402590 | 0.68 | CRHBP (0.54) | ALDH1A1GAATSHRKDM4ECRHBP | |
| SCHEMBL9875296 | 0.67 | CRHBP (0.60) | ALDH1A1TSHRKDM4ECRHBPCRHR2 | |
| SCHEMBL10693569 | 0.67 | TSHR (0.40) | ALDH1A1GAATSHRKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266060-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-05-04 | — | — | EP | disclosed |