Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554326 | 0.86 | ALDH1A1 (0.70) | NPC1RAB9ATSHRMAPK10ALDH1A1 | |
| SCHEMBL2557966 | 0.83 | MAPT (0.60) | NPC1RAB9AMAPK10ALDH1A1MAPT | |
| SCHEMBL14818749 | 0.82 | TSHR (0.68) | TSHRALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL11359123 | 0.81 | POLB (0.56) | RAB9ATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL9400497 | 0.81 | RAB9A (0.78) | NPC1RAB9ATSHRMAPK10ALDH1A1 | |
| SCHEMBL9312836 | 0.79 | HDAC3 (0.67) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL10694565 | 0.79 | SMN1; SMN2 (0.69) | NPC1RAB9ATSHRALDH1A1HSD17B10 | |
| SCHEMBL6032429 | 0.79 | HCAR2 (0.81) | NPC1RAB9ATSHRMAPK10ALDH1A1 | |
| SCHEMBL14076129 | 0.79 | NPC1 (0.58) | NPC1RAB9ATSHRMAPK10ALDH1A1 | |
| SCHEMBL10693582 | 0.79 | TDP1 (0.61) | RAB9AALDH1A1MAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |