Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694568 | 0.84 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL9503442 | 0.84 | CYP2D6 (0.66) | ALDH1A1MAPTLMNAPOLBNPSR1 | |
| SCHEMBL12282275 | 0.81 | PKM (0.64) | ALDH1A1LMNAPOLBKMT2ARAB9A | |
| SCHEMBL28736640 | 0.81 | PKM (0.51) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL28736638 | 0.81 | PKM (0.51) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL10694396 | 0.79 | KLK7 (0.60) | KMT2AMEN1PKMTSHR | |
| SCHEMBL10693263 | 0.78 | PKM (0.51) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL28541441 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAPOLBNPSR1 | |
| SCHEMBL27411599 | 0.77 | MEN1 (0.60) | ALDH1A1MAPTLMNAPOLBNPSR1 | |
| SCHEMBL18554631 | 0.77 | PKM (0.50) | ALDH1A1LMNAPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |