Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282275 | 0.83 | PKM (0.64) | PKMLMNAKMT2AGAAALDH1A1 | |
| SCHEMBL13485414 | 0.81 | CHRM1 (0.51) | CHRM1LMNAMEN1KMT2AGAA | |
| SCHEMBL10694568 | 0.81 | ALDH1A1 (0.57) | PKMMTNR1AMTNR1BLMNAMEN1 | |
| SCHEMBL10695946 | 0.80 | POLB (0.57) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL2844450 | 0.80 | HDAC7 (0.55) | MTNR1AMTNR1BCHRM1KMT2AGAA | |
| SCHEMBL18554631 | 0.79 | PKM (0.50) | PKMLMNAMEN1KMT2AGPR88 | |
| SCHEMBL8449506 | 0.79 | MTNR1A (0.51) | PKMMTNR1AMTNR1BLTB4RLTB4R2 | |
| SCHEMBL10693587 | 0.78 | ALDH1A1 (0.62) | PKMLMNAMEN1KMT2AGAA | |
| SCHEMBL10603038 | 0.78 | CHRM1 (0.51) | MTNR1AMTNR1BCHRM1LTB4RLTB4R2 | |
| SCHEMBL15333659 | 0.77 | MTNR1A (0.50) | PKMMTNR1AMTNR1BLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |