Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | KLK7 | P49862 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502663 | 0.87 | CYP2D6 (0.55) | CYP2D6KMT2AKLK7PKMALDH1A1 | |
| SCHEMBL18134734 | 0.84 | PKM (0.59) | CYP2D6KMT2AKLK7PKMALDH1A1 | |
| SCHEMBL4158526 | 0.84 | PKM (0.62) | KMT2AKLK7PKMALDH1A1MEN1 | |
| SCHEMBL4158522 | 0.84 | PKM (0.62) | KMT2AKLK7PKMALDH1A1MEN1 | |
| SCHEMBL4162007 | 0.84 | PKM (0.62) | KMT2AKLK7PKMALDH1A1MEN1 | |
| SCHEMBL10693587 | 0.84 | ALDH1A1 (0.62) | CYP2D6KMT2APKMALDH1A1POLB | |
| SCHEMBL9502642 | 0.79 | PKM (0.60) | KMT2AKLK7PKMALDH1A1MEN1 | |
| SCHEMBL7599647 | 0.77 | KMT2A (0.51) | CYP2D6KMT2AALDH1A1POLBMEN1 | |
| SCHEMBL18134893 | 0.76 | PKM (0.67) | KMT2AKLK7PKMALDH1A1MEN1 | |
| SCHEMBL10692649 | 0.76 | PKM (0.76) | KMT2AKLK7PKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376852-B1 | MICROGRANULES ESSENTIALLY CONSISTING OF TRIGLYCERIDES OF SATURATED FATTY ACIDS LOADED WITH AN ACTIVE SUBSTANCE, AND THEIR TOPICAL THERAPEUTICAL USE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-06-23 | — | — | EP | claimed |