Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321345 | 0.94 | CHRNA7 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5030270 | 0.89 | CHRNB2 (0.56) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6889363 | 0.89 | CHRNB2 (0.56) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4061901 | 0.87 | CHRNB2 (0.57) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6852321 | 0.87 | LMNA (0.64) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL320403 | 0.85 | CHRNA7 (0.58) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4059613 | 0.83 | RARB (0.53) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6392369 | 0.83 | MAOB (0.63) | SMN1; SMN2MAOAMAOB | |
| SCHEMBL18854655 | 0.82 | LTA4H (0.59) | CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL5677947 | 0.81 | LMNA (0.62) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256303-A2 | Liquid crystal compounds having fluorine-containing core | POLAROID CORPORATION (US) | 1988-02-24 | — | — | EP | disclosed |